Human TREK2, a stretch- and arachidonic acid-sensitive K+ channel activated by inhalational anesthetics and niluzole
US6962976B2 · kind B2 · utility
0Cited by
1References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 27, 2001 |
| Grant date | Nov 8, 2005 |
| Priority date | — |
| Expiry date | Sep 2, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P23/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to a protein including a mammalian K+ channel with two pore domains, designated TREK2, that produces currents whose current-voltage relationship is weakly inward rectifying in high symmetrical K+ conditions. This invention further relates to the isolation and characterization of such protein, as well as a method using TREK2 to identify bioactive compounds having anesthetic properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.