Patent · US Expired

Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors

US6963770B2 · kind B2 · utility

91Cited by
128References
39Claims
0Family size

Assignees

Inventors

Key dates

Filing dateApr 24, 2003
Grant dateNov 8, 2005
Priority date
Expiry dateFeb 23, 2024

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S128/92
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Methods of monitoring and evaluating the status of a tumor undergoing treatment includes monitoring in vivo at least one physiological parameter associated with a tumor in a subject undergoing treatment, transmitting data from an in situ located sensor to a receiver external of the subject, analyzing the transmitted data, repeating the monitoring and transmitting steps at sequential points in time and evaluating a treatment strategy. The method provides dynamic tracking of the monitored parameters over time. The method can also include identifying in a substantially real time manner when conditions are favorable for treatment and when conditions are unfavorable for treatment and can verify or quantify how much of a known drug dose or radiation dose was actually received at the tumor. The method can include remote transmission from a non-clinical site to allow oversight of the tumor's condition even during non-active treatment periods (in between active treatments). The disclosure also includes monitoring systems with in situ in vivo biocompatible sensors and telemetry based operations and related computer program products.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.