Method and apparatus for performing multiple processing steps on a sample in a single vessel
US6964867B2 · kind B2 · utility
17Cited by
5References
16Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 18, 2002 |
| Grant date | Nov 15, 2005 |
| Priority date | — |
| Expiry date | Jul 16, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M47/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method is provided for determining crystallization conditions for a protein, the method comprising: performing in a same fermentation apparatus 2 or more separate fermentations where each fermentation comprises cells expressing a protein to be purified and has a fermentation volume of less than 500 mL; purifying the expressed protein from the separate fermentations; and determining crystallization conditions for the purified protein by submicroliter crystallization experiments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.