Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments

US6964966B2 · kind B2 · utility

Assignee

• Wockhardt Limited · IN

Inventors

• Noel De Souza · Mumbai, IN
• Mahesh Vithalbhai Patel · Aurangabad, IN
• Prasad Keshav Deshpande · Aurangabad, IN
• Shiv Kumar Agarwal · Chennai, IN
• Shrikant Gupte · Aurangabad, IN
• Dilip J. Upadhyay · Thane, IN
• Satish Bhawsar · Aurangabad, IN
• Rupinder K. Beri · Aurangabad, IN
• Kandepu Sreenivas · Aurangabad, IN
• Sheela Chandrasekharan Nair · Aurangabad, IN
• Milind Shukla · Aurangabad, IN
• Yati Chugh · Panchkula, IN
• Nitin Shetty · Kalyan-Dombivli, IN
• Ravindra Dattatraya Yeole · Aurangabad, IN
• M. Madhav Reddy · Aurangabad, IN

Key dates

• Filing date: Apr 23, 2002
• Grant date: Nov 15, 2005
• Expiry date: Jun 1, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.