Bicyclic androgen and progesterone receptor modulator compounds and methods
US6964973B2 · kind B2 · utility
43Cited by
111References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 18, 2002 |
| Grant date | Nov 15, 2005 |
| Priority date | — |
| Expiry date | Nov 18, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by AR and PR. More particularly, the invention relates to nonsteroidal compounds and compositions that are high affinity, high specificity agonists, partial agonists (i.e., partial activators and/or tissue-specific activators) and antagonists for AR and PR. Also provided are methods of making such compounds and pharmaceutical compositions, as well as critical intermediates used in their synthesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.