Method of purification of molecules using unbranched terminal alkyldiols
US6966992B2 · kind B2 · utility
2Cited by
5References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 19, 2001 |
| Grant date | Nov 22, 2005 |
| Priority date | — |
| Expiry date | Aug 28, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/12
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The current invention provides methods for molecule purification by RP-LC and RP-HPLC that uses unbranched terminal alkyldiols as eluting solvents. In particular, the present invention purifies molecules, particularly proteins and peptides, on reverse phase liquid chromatography columns using a buffer containing either 1,5 pentanediol, 1,6 hexanediol or 1,7 heptanediol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.