Oxygen carrier system, artificial oxygen carrier, and reducing agent
US6967020B2 · kind B2 · utility
2Cited by
0References
18Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 27, 2004 |
| Grant date | Nov 22, 2005 |
| Priority date | — |
| Expiry date | Aug 27, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An oxygen carrier system includes an artificial oxygen carrier including hemoglobin vesicles encapsulating hemoglobin and an intermediate electron mediator having a standard electrode potential of 0.05 V to 0.56 V (vs. the standard hydrogen electrode) in the vesicles, and a reducing agent which is added to an external aqueous phase of the hemoglobin vesicle to reduce methemoglobin when the hemoglobin encapsulated in the hemoglobin vesicle is oxidized to the methemoglobin. The reducing agent has, as an active component, at least one compound selected from the group consisting of a thiol compound and a reducing sugar.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.