Tricyclic compounds protein kinase inhibitors for enhancing the efficacy of anti-neoplastic agents and radiation therapy
US6967198B2 · kind B2 · utility
11Cited by
4References
37Claims
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Key dates
| Filing date | Jan 9, 2004 |
| Grant date | Nov 22, 2005 |
| Priority date | — |
| Expiry date | Jan 9, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Protein kinase, such as CHK-1, inhibiting tricyclic compounds of the following formula (wherein R2, R3 and R4 are as defined in the specification) pharmaceutical compositions containing effective amounts of said compounds or their salts are useful as a single agent or in combination with an anti-neoplastic agent or therapeutic radiation having an anti-neoplastic effect for treating diseases or conditions such as cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.