Methods to prepare cells comprising heterologous polyketide synthase expression systems

US6969611B2 · kind B2 · utility

Assignees

• The Board of Trustees of the Leland Stanford Univeristy · US
• The John Innes Institute · GB

Inventors

• Chaitan Khosla · Stanford, US
• David A. Hopwood · Norwich, GB
• Suzanne Ebert-Khosla · Stanford, US
• Robert McDaniel · Palo Alto, US
• Hong Fu · Chongqing, CN
• Camilla Kao · Palo Alto, US

Key dates

• Filing date: Aug 8, 2001
• Grant date: Nov 29, 2005
• Expiry date: Dec 11, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P19/62
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Novel polyketides and novel methods of efficiently producing both new and known polyketides, using recombinant technology, are disclosed. In particular, a novel host-vector system is described which is used to produce polyketide synthases which in turn catalyze the production of a variety of polyketides.