Optically active carbonates as precursors of (+)-zopiclone
US6969767B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 2, 2003 |
| Grant date | Nov 29, 2005 |
| Priority date | — |
| Expiry date | May 12, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
In the present invention new compounds of formula II, in enantiomerically enriched forms, are described for the first time, where R1 is chloroalkyl. The present invention also includes several new enzymatic processes for the resolution of the enantiomers of the aforementioned carbonates of formula II from the corresponding racemic mixture. The transformation of these carbonates into zopiclone enantiomerically enriched, constitutes an additional aspect of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.