Insoluble drug delivery

US6974593B2 · kind B2 · utility

Assignees

• JAGOTEC AG · CH
• The Board of Regents of the University of Texas System · US

Inventors

• Inge B Henriksen · Durham, US
• Awadesh K. Mishra · Durham, US
• Gary W. Pace · Winchester, US
• Keith P. Johnston · Austin, US
• Simon Mawson · Charleston, US

Key dates

• Filing date: Jun 9, 2003
• Grant date: Dec 13, 2005
• Expiry date: Jun 9, 2023

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S977/906
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Particles of water insoluble biologically active compounds, particularly water-insoluble drugs, with an average size of 100 nm to about 300 nm, are prepared by dissolving the compound in a solution then spraying the solution into compressed gaz, liquid or supercritical fluid in the presence of appropriate surface modifiers.