Soluble interleukin-1 receptor accessory molecule
US6974682B1 · kind B1 · utility
5Cited by
0References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 26, 1997 |
| Grant date | Dec 13, 2005 |
| Priority date | — |
| Expiry date | Aug 26, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/7155
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a novel soluble IL-1 receptor accessory molecule (IL-1R AcM) protein which is a member of the Ig superfamily. In particular, isolated nucleic acid molecules are provided encoding the human IL-1R AcM protein IL-1R AcM polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. Screening methods are further provided for identifying agonist and antagonists of IL-1 signal transduction. The invention further relates to methods for treating physiologic and pathologic disease conditions with IL-1R AcM antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.