Therapeutic polypeptides, nucleic acids encoding same, and methods of use

US6974684B2 · kind B2 · utility

Assignee

• Curagen Corporation · US

Inventors

• David Anderson · Gladsmuir, GB
• John P. Alsobrook II · Madison, US
• Ferenc Boldog · North Haven, US
• Catherine Burgess · Wethersfield, US
• Stacie Casman · North Haven, US
• Shlomit Edinger · New Haven, US
• Esha Gangolli · Madison, US
• Linda Gorman · Branford, US
• Xiaojia Guo · Branford, US
• Nikolai Khramtsov · Branford, US
• Denise Lepley · Branford, US
• John MacDougall · Hamden, US
• Carol Pena · New Haven, US
• John Peyman · New Haven, US
• Meera Patturajan · Branford, US
• Daniel Rieger · Cape Elizabeth, US
• Richard Shimkets · West Haven, US
• Glennda Smithson · Guilford, US
• Kimberly Spytek · New Haven, US
• Corine Vernet · North Branford, US
• Edward Voss · Wallingford, US
• Mei Zhong · Branford, US

Key dates

• Filing date: Aug 1, 2002
• Grant date: Dec 13, 2005
• Expiry date: Jun 25, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.