Patent · US Expired

Alpha 1-antitrypsin preparation as well as a method for producing the same

US6974792B2 · kind B2 · utility

12Cited by

2References

15Claims

0Family size

Assignee

Baxter Aktiengesellschaft · AT

Inventors

Erwin Mattes · Perchtoldsdorf, AT
H. Peter Matthiessen · Wien, AT

Key dates

Filing date	Sep 24, 2001
Grant date	Dec 13, 2005
Priority date	—
Expiry date	Dec 22, 2022

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A native, chromatographically purified α1-AT preparation having a purity of at least 0.7 PU/mg protein and a relative plasma α1-AT activity of at least 120% is disclosed. The ratio of active to inactive α1-AT is higher than in plasma.Furthermore, a method of producing this preparation is disclosed, as well as the use of a carrier material, e.g. an inorganic carrier material such as hydroxylapatite for separating active α1-AT from inactive α1-AT.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.