Configuration of glycosaminoglycans
US6974805B2 · kind B2 · utility
3Cited by
2References
2Claims
0Family size
Inventor
Key dates
| Filing date | Aug 1, 2003 |
| Grant date | Dec 13, 2005 |
| Priority date | — |
| Expiry date | Aug 1, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/726
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides stable glycosaminoglycan (GSG) structures and methods of use of such GAG structures. These structures comprise a core of free GAG, a coating of crosslinked GAG surrounding the core, and a layer of a positively charged moiety surrounding the crosslinked GAG layer. These GAG structures provide improved stability, both in in vivo and external use. Furthermore, resurfacing of the structures provides improved cell adhesion and thus improved delivery of the GAG into living cells and tissues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.