Patent · US Expired

Parallel detection chromatography systems

US6976384B2 · kind B2 · utility

62Cited by
50References
31Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 30, 2003
Grant dateDec 20, 2005
Priority date—
Expiry dateOct 30, 2023

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2030/8881
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

High throughput liquid chromatography systems include multiple separation columns and multiple flow-through detection regions in sensory communication with a common radiation source and a multi-channel detector. Preferred detector types include a multi-anode photomultiplier tube, a charge-coupled device detector, a diode array, and a photodiode array. In certain embodiments, separation columns are microfluidic and integrated into a unitary microfluidic device. The optical path through a detection region is preferably coaxial with the path of eluate flow along a flow axis through a detection region. On-board or off-board detection regions may be provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.