Determination of testosterone by mass spectrometry
US6977143B1 · kind B1 · utility
65Cited by
9References
39Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 2, 2003 |
| Grant date | Dec 20, 2005 |
| Priority date | — |
| Expiry date | Dec 30, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/200833
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided are methods for determining the presence or amount of testosterone in a test sample, comprising ionizing all or a portion of the testosterone present in the sample to produce one or more testosterone ions that are detectable in a mass spectrometer. All or a portion of the testosterone present in the sample is ionized to produce one or more testosterone ions, which may be isolated and fragmented to produce precursor ions. A separately detectable internal testosterone standard can be provided in the sample. In a preferred embodiment, the reference is 2, 2, 4, 6, 6-d5 testosterone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.