Small triplex forming PNA oligos
US6979536B1 · kind B1 · utility
1Cited by
9References
49Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 21, 1998 |
| Grant date | Dec 27, 2005 |
| Priority date | — |
| Expiry date | Sep 10, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6839
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for the determination of nucleic acids which is highly specific and simple comprises the formation of a triple stranded binding complex including two separate, different probe molecules and detecting the formation of the complex via the inclusion of one of the probes. The method can be used to differentiate between nucleic acids having a single base difference in sequence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.