Arylated furan- and thiophenecarboxamides, processes for their preparation, their use as medicaments, and pharmaceutical preparations comprising them

US6982279B2 · kind B2 · utility

Assignee

• Aventis Pharma Deutschland GmbH · DE

Inventors

• Stefan Peukert · Frankfurt am Main, DE
• Joachim Brendel · Bad Vilbel, DE
• Horst Hemmerle · Lorsch, DE
• Heinz-Werner Kleemann · Bischofsheim, DE

Key dates

• Filing date: Dec 12, 2001
• Grant date: Jan 3, 2006
• Expiry date: Apr 30, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D307/68
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formulae IA and Ib. in which X, R(1), R(2), R(3), R(4), R(5), R(6), R(7), R(30) and R(31) have the meanings indicated in the claims, are very particularly suitable as novel antiarrhythmic active compounds, in particular for the treatment and prophylaxis of atrial arrhythmias, e.g. atrial fibrillation (AF) or atrial flutters.