Altered antibodies
US6982321B2 · kind B2 · utility
408Cited by
11References
24Claims
0Family size
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Key dates
| Filing date | Jan 24, 2003 |
| Grant date | Jan 3, 2006 |
| Priority date | — |
| Expiry date | Jun 17, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An altered antibody is produced by replacing the complementarity determining regions (CDRs) of a variable region of an immunoglobulin (Ig) with the CDRs from an Ig of different specificity, using recombinant DNA techniques. The gene coding sequence for producing the altered antibody may be produced by site-directed mutagenesis using long oligonucleotides or using gene synthesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.