α-tocopherol transport protein knockout animal
US6982362B1 · kind B1 · utility
3Cited by
0References
7Claims
0Family size
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Key dates
| Filing date | Aug 24, 2000 |
| Grant date | Jan 3, 2006 |
| Priority date | — |
| Expiry date | Aug 24, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0306
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a knockout animal artificially modified to inhibit α-TTP gene expression. This animal is useful as a tool for understanding mechanisms for the development of familial isolated vitamin E deficiency and other diseases induced by oxidative stress (e.g., arteriosclerosis, diabetes). It is also useful as a tool for developing a therapeutic agent for these diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.