Patent · US Expired

Mitochondrially targeted antioxidants

US6984636B2 · kind B2 · utility

13Cited by

4References

11Claims

0Family size

Assignees

Medical Research Council · GB
University of Otago · NZ

Inventors

Michael Patrick Murphy · Arlington, US
Robin Smith · Dunedin, NZ

Key dates

Filing date	Aug 12, 2002
Grant date	Jan 10, 2006
Priority date	—
Expiry date	Apr 10, 2023

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F13/005
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides mitochondrially targeted antioxidant compounds comprising a lipophilic cation moiety covalently coupled to an antioxidant moiety which is either a superoxide dismutase (SOD) mimetic or a glutathione peroxidase mimetic. These compounds can be used to treat patients who would benefit from the reduction of oxidative stress.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.