Carboline derivatives as PDE5 inhibitors

US6984641B2 · kind B2 · utility

Assignee

• Lilly ICOS LLC · US

Inventors

• Mark W. Orme · Seattle, US
• Jason Scott Sawyer · Indianapolis, US
• Alain Claude-Marie Daugan · Les Ulis, FR
• Agnes Bombrun · Paris, FR
• Francoise Gellibert · Cachan, FR
• Lisa M. Schultze · Woodinville, US
• Raymond F. Brown · Fishers, US
• Romain Luc Marie Gosmini · Les Ulis, FR

Key dates

• Filing date: May 2, 2002
• Grant date: Jan 10, 2006
• Expiry date: May 17, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Selective inhibitors of cGMP-specific PDE, and use of the compounds and salts and solvates thereof as therapeutic agents, are disclosed.