Anti-human VEGF receptor Flt-1 monoclonal antibody
US6986890B1 · kind B1 · utility
57Cited by
9References
6Claims
0Family size
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Key dates
| Filing date | Dec 3, 1999 |
| Grant date | Jan 17, 2006 |
| Priority date | — |
| Expiry date | Dec 3, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2799/026
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides an antibody or peptide which immunologically reacts with human VEGF receptor Flt-1 and cells in which human VEGF receptor Flt-1 is expressed on the cell surface and an antibody or peptide which inhibits binding of human VEGF to human VEGF receptor Flt-1. It also provides a means for the diagnosis or treatment of diseases in which their morbid states progress by abnormal angiogenesis, such as proliferation or metastasis of solid tumors, arthritis in rheumatoid arthritis, diabetic retinopathy, retinopathy of prematurity, psoriasis, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.