Process for producing multiple nucleic acid copies in vivo using a protein-nucleic acid construct

US6986985B1 · kind B1 · utility

Assignee

• ENZO LIFE SCIENCES, INC. · US

Inventors

• Dean Engelhardt · New York, US
• Jannis G. Stavrianopoulos · Bay Shore, US
• Elazar Rabbani · New York, US
• James J. Donegan · Amesbury, US

Key dates

• Filing date: Mar 3, 1998
• Grant date: Jan 17, 2006
• Expiry date: Mar 3, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N15/10
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

This invention provides in vitro processes for producing copies of specific nucleic acids using protein-nucleic acid constructs which are part of conjugates which are introduced into cells. Illustrative of the elements useful in these constructs for producing copies of specific nucleic acids are promoters, sequences coding for proteins or providing templates for transcription, and RNA polymerases.