Method for screening using an OAT1 transporter protein
US6986997B1 · kind B1 · utility
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7Claims
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Key dates
| Filing date | May 18, 1998 |
| Grant date | Jan 17, 2006 |
| Priority date | — |
| Expiry date | May 18, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/47
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A protein capable of transporting organic anions having amino acid sequences represented by SEQ ID NO: 1 or 2 or amino acid sequences derived therefrom by deletion, substitution or addition of one or more amino acid residues; and a gene coding for the protein. The protein and gene therefore are useful in vitro analysis of drug release and drug—drug interactions and development of method for screening drugs useful for preventing nephrotoxicity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.