Matrix metalloproteinase inhibitors
US6989139B2 · kind B2 · utility
1Cited by
7References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 14, 2001 |
| Grant date | Jan 24, 2006 |
| Priority date | — |
| Expiry date | Jun 19, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/6527
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Thus the present invention describes novel compounds comprising 1-10 targeting moieties; a chelator (Ch); and 0-1 linking groups (Ln) between the targeting moiety and chelator; wherein the targeting moiety is a matrix metalloproteinase inhibitor; and wherein the chelator is capable of conjugating to a cytotoxic radioisotope. The present invention also provides novel compositions of the compounds of the invention, kits and their uses in treatment of diseases associated with MMPs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.