Subfamily of RNA helicases which are modulators of the fidelity of translation termination and uses thereof
US6989256B2 · kind B2 · utility
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Key dates
| Filing date | Aug 28, 2003 |
| Grant date | Jan 24, 2006 |
| Priority date | — |
| Expiry date | Oct 15, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An isolated multiprotein complex of S. cerevisiae components is provided that is effective to modulate peptidyl transferase activity during translation. This complex includes a Modulator of Translation Termination protein (Mtt1p, also referred to as helicase B), a Upf1 protein, a peptidyl eukaryotic release factor 1 (eRF1) and a peptidyl eukaryotic release factor 3 (eRF3).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.