Isoprenoid production

US6989257B2 · kind B2 · utility

Assignee

• DSM IP ASSETS B.V. · NL

Inventors

• Alan Berry · Loomis, US
• Werner Bretzel · Soest, DE
• Markus Humbelin · Basel, CH
• Rual Lopez-Ulibarri · Kaiseraugst, CH
• Anne Françoise Mayer · Basel, CH
• Alexei A. Yeliseev · Lafayette, US

Key dates

• Filing date: Jun 5, 2002
• Grant date: Jan 24, 2006
• Expiry date: Jul 3, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/01
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Isolated polynucleotides encoding polypeptides having the activity of enzymes in the mevalonate pathway are provided. These sequences are useful for recombinantly producing isoprenoid compounds, such as carotenoids, in particular zeaxanthin. Expression vectors, cultured cells, and methods of making isoprenoid compounds are also provided.