Synthesis of 2-chloromethyl-6-methylbenzoic ester

US6989462B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Claus-Jürgen Maier · Hemsbach, DE
• Tobias Metzenthin · Frankfurt, DE
• Joachim Graeser · Kelsterbach, DE
• Richard Bicker · Liederbach, DE
• Javier Manero · Frankfurt, DE

Key dates

• Filing date: Mar 18, 2004
• Grant date: Jan 24, 2006
• Expiry date: Mar 18, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C69/76
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process is described for preparing compounds of formula (I) where R is H, optionally halogen-substituted alkyl, cycloalkyl, aryl, alkyl-aryl or heteroaryl, and, in alkyl and cycloalkyl, one or more CH2 groups may be replaced by —O—. The compounds of the formula (I) are valuable intermediates in the synthesis of PPAR agonists.