Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays
US6991907B1 · kind B1 · utility
30Cited by
5References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 12, 2000 |
| Grant date | Jan 31, 2006 |
| Priority date | — |
| Expiry date | Jun 4, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/819
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Antibodies and methods are described for the detection and quantitation of cardiac specific troponin I in samples. Cardiac-specific troponin isoforms exist in various forms in the blood, including free and complexed forms. By selecting antibodies that are insensitive and/or sensitive to these various forms, the present invention can provide immunoassays that more accurately reflect the clinical state of an individual. These described antibodies and methods can be used for providing indicators of myocardial infarction and other cardiac pathologies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.