Gridlock nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
US6991936B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Feb 10, 2003 |
| Grant date | Jan 31, 2006 |
| Priority date | — |
| Expiry date | Jul 11, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a novel gene, gridlock, and its encoded protein. gridlock plays a role in vascular development and modeling, and a mutation in gridlock has been associated with an aortic arch disease, coarctation. Thus, gridlock nucleic acid molecules and polypeptides can be used in methods of diagnosing, treating, and preventing gridlock-related diseases and conditions, such as aortic arch diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.