Spirocyclic ligands for sigma receptors, and libraries and methods of use thereof
US6992077B2 · kind B2 · utility
43Cited by
2References
90Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 13, 2004 |
| Grant date | Jan 31, 2006 |
| Priority date | — |
| Expiry date | Aug 16, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
One aspect of the present invention relates to spirocyclic compounds. Another aspect of the present invention relates to the use of the spirocyclic compounds as ligands for mammalian G-protein-coupled receptors or sigma receptors. The present invention also relates to methods of modulating the activity of a G-protein-coupled receptor or a sigma receptor in a mammal using the spirocyclic compounds of the present invention. The present invention also relates to methods of treating various diseases in a mammal using the spirocyclic compounds of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.