Growth hormone secretagogues

US6992097B2 · kind B2 · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Kenneth Lee Hauser · Greencastle, US
• Jeffrey A. Dodge · Indianapolis, US
• Mark L. Heiman · Indianapolis, US
• Scott Alan Jones · Indianapolis, US
• Charles A. Alt · Greenwood, US
• Henry U. Bryant · Indianapolis, US
• Jeffrey Daniel Cohen · Indianapolis, US
• James Densmore Copp · Silverthorne, US
• Kennan J. Fahey · Indianapolis, US
• William Harlan Gritton · Zionsville, US
• Louis Nickolaus Jungheim · Indianapolis, US
• Joseph Kennedy · Scotts Valley, US
• Charles Willis Lugar, III · McCordsville, US
• Brian S. Muehl · Indianapolis, US
• Alan David Palkowitz · Carmel, US
• Andrew Michael Ratz · Greenwood, US
• Gary A. Rhodes · Indianapolis, US
• Roger L. Robey · Greenwood, US
• David E. Seyler · Greenfield, US
• Timothy Alan Shepherd · Indianapolis, US
• Kenneth Jeff Thrasher · Indianapolis, US
• William George Trankle · Southport, US

Key dates

• Filing date: Jun 3, 2003
• Grant date: Jan 31, 2006
• Expiry date: Aug 8, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.