Patent · US Expired

Benzamide derivatives, processes for their preparation, and their pharmaceutical use

US6992103B2 · kind B2 · utility

22Cited by
1References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 29, 2002
Grant dateJan 31, 2006
Priority date
Expiry dateNov 29, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D263/22
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to novel hydroxyethylene compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.