Thiol-based NAALADase inhibitors
US6992215B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Oct 7, 2004 |
| Grant date | Jan 31, 2006 |
| Priority date | — |
| Expiry date | Oct 8, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/65
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-β activity, inhibiting angiogenesis, and treating glutamate abnormalities, diabetic neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.