Systems for applying cross-linked mechanical barriers
US6994686B2 · kind B2 · utility
86Cited by
74References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 28, 2001 |
| Grant date | Feb 7, 2006 |
| Priority date | — |
| Expiry date | Feb 28, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/36
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A delivery device applies a biocompatible and biodegradable barrier material to a tissue region, e.g., to seal a vascular puncture site. The material comprises two liquid components, which are pre-packaged in individual dispensers. Upon mixing, the liquid components cross-link to create a barrier matrix. A holder attaches to the delivery device. The holder mutually supports the first and second dispensers while the protein solution and polymer solution are conveyed from the dispensers into a fluid delivery channel. The protein and polymer solutions mix as a result of flow through the channel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.