Patent · US Expired

Active modified hedgehog proteins

US6994990B1 · kind B1 · utility

1Cited by

3References

6Claims

0Family size

Assignee

Curis, Inc. · US

Inventors

Kurt Lang · Penzberg, DE
Ulrike Leser · Munich, DE
Tilman Seytter · Gräfelfing, DE

Key dates

Filing date	Nov 24, 1998
Grant date	Feb 7, 2006
Priority date	—
Expiry date	Nov 21, 2019

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2799/026
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides isolated highly active hedgehog proteins esterified with a fatty acid having from 14 to 20 carbon atoms at the N-terminal domain of the protein. The highly active hh proteins are particularly useful therapeutic agents for treating bone disorders and neurodegenerative diseases. Methods for obtaining the highly active modified hedgehog proteins are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.