Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
US6995172B2 · kind B2 · utility
11Cited by
29References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 21, 2004 |
| Grant date | Feb 7, 2006 |
| Priority date | — |
| Expiry date | Jan 26, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application describes lactam-containing compounds and derivatives thereof of Formula I:P4-P-M-M4 Ior pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5–7 membered carbocycle or heterocycle and ring M is a 5–7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.