Antibodies that recognize and bind phosphorylated human glucocorticoid receptor and methods of using same
US6995243B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Jul 30, 2003 |
| Grant date | Feb 7, 2006 |
| Priority date | — |
| Expiry date | Sep 8, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A molecule containing the antigen binding portion of an antibody specific for human glucocorticoid receptor phosphorylated at residue Ser211, Ser226 or Ser203 is obtained and a method of determining the presence of activated glucocorticoid receptors in cells from human glucocorticoid responsive tissue and a method of screening for a glucocorticoid agonist using the molecule, which is preferably an antibody, are provided in the present invention.
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