Gene involved in CADASIL, method of diagnosis and therapeutic application
US6995257B1 · kind B1 · utility
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5Claims
0Family size
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Key dates
| Filing date | Jul 7, 2000 |
| Grant date | Feb 7, 2006 |
| Priority date | — |
| Expiry date | Jul 7, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.