Reduction of matrix interference for MALDI mass spectrometry analysis
US6995363B2 · kind B2 · utility
9Cited by
12References
12Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Aug 9, 2004 |
| Grant date | Feb 7, 2006 |
| Priority date | — |
| Expiry date | Dec 1, 2024 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/31663
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
A MALDI plate suitable for MS or MS-MS analysis provided with a composite coating that comprises a hydrophobic coating and a thin layer coating of a mixture of a MALDI matrix material and an intercalating agent such as a polymer is disclosed. A MALDI plate produced in accordance with the present teachings is useful for suppression of matrix ions in the low mass region (<1,000 daltons) of a MALDI-MS spectrum.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.