Methods for treating solid tumors using neutron therapy
US6997861B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 27, 2004 |
| Grant date | Feb 14, 2006 |
| Priority date | — |
| Expiry date | Jan 27, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2005/109
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The invention described herein comprises a method of treating a subject having a disorder characterized by the presence of one or more tumors comprising inserting a miniaturized concentrated neutron emitting source into said tumor(s) for a time sufficient to irradiate the cells of the tumor(s). The invention method can be employed in the treatment of both malignant and non-malignant tumors and is especially useful in the treatment of malignant tumors found in the brain, prostate, and other internal organs. A preferred neutron source is californium-252. The majority of the tumor can be surgically removed prior to insertion of the neutron emitting source. In a further embodiment of the invention, a neutron capture compound can be localized to the cells of the tumor prior to insertion of the miniaturized neutron emitting source in order to augment the effects of neutron therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.