Antibody specific for presenilin 1 and method of use thereof
US6998467B1 · kind B1 · utility
4Cited by
2References
15Claims
0Family size
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Key dates
| Filing date | Oct 12, 2000 |
| Grant date | Feb 14, 2006 |
| Priority date | — |
| Expiry date | Nov 1, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/34
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention describes the identification, isolation, cloning, and determination of the Alzheimer Related Membrane Protein (ARMP) gene on chromosome 14 and a related gene, E5-1, on chromosome 1. Normal and mutant copies of both genes are presented. Transcripts and products of these genes are useful in detecting and diagnosing Alzheimer's disease, developing therapeutics for treatment of Alzheimer's disease, as well as the isolation and manufacture of the protein and the construction of transgenic animals expressing the mutant genes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.