Method for performing submicroliter crystallization experiments with high experiment to experiment precision

US7001438B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Bernard D. Santarsiero · San Diego, US
• Raymond C. Stevens · Village of La Jolla, US
• Peter G. Schultz · Village of La Jolla, US
• Joseph M. Jaklevic · Lafayette, US
• Derek T. Yegian · Oakland, US
• Earl Cornell · Antioch, US
• Robert Nordmeyer · Calabasas, US

Key dates

• Filing date: Apr 8, 2002
• Grant date: Feb 21, 2006
• Expiry date: Sep 28, 2022

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/2575
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method is provided for forming crystallization experiments for a molecule, the method comprising forming a plurality of crystallization experiments that comprise a molecule to be crystallized and a composition that varies among the plurality of crystallization experiments, the crystallization experiments having a volume less than 1 microliter, the volumes of the plurality of crystallization experiments varying among the experiments by less than 25 nL.