Expanded porphyrin compositions for tumor inhibition
US7001588B2 · kind B2 · utility
0Cited by
0References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 12, 2003 |
| Grant date | Feb 21, 2006 |
| Priority date | — |
| Expiry date | Sep 16, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D517/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Expanded porphyrin comprising substitutions for at least two NH groups by S, Se or Te are non-photoactive and are selective for binding G-quadruplexes characteristic of the c-MYC control region. Accordingly, these expanded porphyrins are useful to modulate the expression of genes controlled by the formation of c-MYC type G-quadruplexes, such as c-MYC itself.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.