Oncolytic adenovirus
US7001596B1 · kind B1 · utility
26Cited by
8References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 14, 2000 |
| Grant date | Feb 21, 2006 |
| Priority date | — |
| Expiry date | Nov 14, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Viral vectors and methods of making such vectors are described that preferentially kill neoplastic but not normal cells, the preferred vector being an adenovirus that has the endogenous promoters in the E1A and/or E4 regions substituted with a tumor specific promoter which is preferably E2F responsive.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.