Catalytic RNAs with aminoacylation activity
US7001723B1 · kind B1 · utility
1Cited by
6References
9Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 22, 2000 |
| Grant date | Feb 21, 2006 |
| Priority date | — |
| Expiry date | Feb 17, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/12
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides catalytic RNA molecules having cis or trans aminoacylation activity. The catalytic RNA molecules having cis aminoacylation activity comprise a catalytic domain and an aminoacylation domain. The catalytic RNA molecules having trans aminoacylation activity only have the catalytic domain. A method is provided for constructing and screening of these molecules. These molecules are suitable for aminoacylating tRNA-like molecules with specific amino acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.