Epothilon derivatives, method for the production and the use thereof as pharmaceuticals

US7001916B1 · kind B1 · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Ulrich Klar · Berlin, DE
• Werner Skuballa · Berlin, DE
• Bernd Buchmann · Hohen Neuendorf, DE
• Wolfgang Schwede · Berlin, DE
• Michael Schirner · Berlin, DE

Key dates

• Filing date: Feb 11, 2000
• Grant date: Feb 21, 2006
• Expiry date: Feb 11, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D493/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed are epothilone compounds of formula I, which are useful as pharmaceutical compounds for treating, for example, malignant tumors and chronic inflammatory diseases and are useful in anti-angiogenesis therapy.