Down-regulation resistant C3 convertase
US7002001B2 · kind B2 · utility
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Key dates
| Filing date | Jun 6, 2001 |
| Grant date | Feb 21, 2006 |
| Priority date | — |
| Expiry date | Feb 6, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/582
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Native complement pathway proteins modified such that the protein is capable of forming a down-regulation resistant C3 convertase. Preferably the modified protein is a modified human C3 protein. DNA sequences encoding such proteins are also provided, together with DNA constructs. Conjugates comprising such proteins and a specific binding moiety, for example an antibody, are also described, as are uses of such proteins and/or conjugates in therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.